Summary

  • Human biology, specifically neurology, often necessitates the use of human test subjects due to the lack of analogous models in other mammals.
  • Recent developments have seen the creation of assembloids – organoids that simulate multiple aspects of human biology, in this case the somatosensory pathway.
  • Such organoids, cultures grown from human stem cells, can be used to study the development of and the defects within human biological pathways, as well as the testing of therapies.
  • This article summarises the use of organoids and assembloids in medicine, discussing some of the limitations and prospects of the technique.
  • There are hopes that using organoids will provide further insight into genetic causes of tactile deficits and help to model complex diseases.

By Maya Posch

Original Article