Summary

  • In 2022, a clinical trial found a injectable drug called lenacapavir was able to prevent HIV infections in 100% of the women and girls who received it.
  • This week, a small phase I trial found the drug continues to provides protection when injected just once a year.
  • Lenacapavir works by interfering with the virus’s ability to replicate and can be taken daily or yearly.
  • It can also stay in the blood for days or form a depot, gradually releasing the drug over time.
  • The drug is currently awaiting approval by the FDA, with plans for licensing agreements with generic drug manufacturers to provide cheaper options for low- and middle-income countries.
  • However, this is currently under threat due to the Trump administration’s executive order to pause foreign aid.

By Jessica Hamzelou

Original Article